Indiana University Purdue University Indianapolis

Regenerative Biology

Regenerative Biology is the study of the mechanisms by which organisms maintain their tissue structure and regenerate this structure after tissue loss due to injury or disease. Such studies have application to the development of clinical therapies to regenerate tissues that do not normally regenerate or regenerate poorly, and also to design and build bioartificial organs that can replace dysfunctional organs. The field is highly multidisciplinary, drawing on expertise from developmental, cell and molecular biology, chemistry, informatics, mathematics and computer science, and engineering. The application of such studies constitutes the emerging field of regenerative medicine.

The department of Biology currently has seven faculty involved in research on regenerative biology. Teri Belecky-Adams, Ellen Chernoff, Randall Roper, Simon Rhodes and Jason Meyer work on neural regeneration using a range of animal models, including chick, mouse, and amphibian. James Marrs studies auditory development and regeneration in the mouse and Guoli Dai’s research is on mammalian liver regeneration. Jiliang Li works on mammalian bone regeneration and amphibian limb regeneration, respectively. These faculty members have multiple collaborations with investigators in Dentistry, Medicine and Informatics through the Center for Developmental and Regenerative Biology, and with colleagues at other universities. Their funding is derived from multiple government agencies and private foundations. Because of this collaborative network, regenerative biology faculty members have access to a wide variety of technologies, equipment, and laboratory space.

The Department of Biology offers MS and PhD degrees with concentrations in Regenerative Biology and Medicine. We encourage students with good undergraduate preparation to apply to this program through the Department of Biology. For more information see faculty profiles and the website for the Center for Regenerative Biology and Medicine at http://regen.iupui.edu.